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Groningen University Medical Center – Center for Liver, Digestive and Metabolic diseases

Groningen University Medical Center – Center for Liver, Digestive and Metabolic diseases

PO Box 30.001, 9700 RB Groningen
Hanzeplein 1, 9713GZ Groningen, NL

Contact
Bert Groen
a.k.groen@umcg.nl
31(0)503632669

Research line
Health and Disease

Topics
Arteriosclerosis (cholesterol and bile acid metabolism)
Diabetes Mellitus (glucose, lipid metabolism)
men, rats, various mouse models and cell cultures
regulation of metabolic pathways
kinetics of metabolic pathways applying tracer technology
colon delivery device
cholesterol, bile acids, glucose, palmitic acid, stearic acid, oleic acid, urea, bicarbonate, breath CO2
kinetic studies in mouse blood, requiring frequent sampling of minimal blood spots

Isotopes
13C, 15N, 2H

Instruments
GC/C/IRMS, GC/P/IRMS, GC/MS, LC/MS/MS

Agilent 6890 GC/ Finnigan DeltaplusXL IRMS with CTC Pal autosampler
Two Agilent 6890 GC/ 5975 quadrupole MS with CTC Pal auto sampler
Perkin ElmerLC/API 3000 MS/MS with Perkin Elmer auto sampler
Shimadzu LC/API 3000 MS/MS with Shimadzu auto sampler

KU Leuven – Department of Clinical and Experimental Medicine

KU Leuven – Department of Clinical and Experimental Medicine

O&N1, box 701 / Herestraat 49, 3000 Leuven, B

Contact
Prof. Kristin Verbeke
kristin.verbeke@med.kuleuven.be
32(0)16330150

Research line
Health and disease

Topics
Estimation of colonic short chain fatty acid production
Analysis of colonic ammonia metabolism using 15N-labelled lactose ureide
Breath tests using 13C-labelled substrates

Isotopes
13C, 15N

Instruments
GC/IRMS, EA/C/IRMS, GC/C/IRMS

ABCA (Sercon, UK)
ANCA (Sercon, UK)
GC-C-IRMS (Thermo)

KU Leuven – Department of Earth & Environmental Sciences

KU Leuven – Department of Earth & Environmental Sciences

Celestijnenlaan 200E, 3001 Leuven, B

Contact
Steven Bouillon
Steven.Bouillon@ees.kuleuven.be
32(0)498513608

Research line
Ecology, Biogeochemistry

Topics
Biogeochemistry
Terrestrial and aquatic biogeochemistry – both natural abundance and tracer experiments.

 Isotopes
13C, 15N, 18O, 32S

δ13C (organic matter, dissolved inorganic carbon, dissolved organic carbon
dissolved CH4, carbonates, specific compounds)
δ15N (organic matter, dissolved N2)
δ18O (H2O, dissolved O2)
δ34S (organic matter)

Instruments
EA/C/IRMS, GC/C/IRMS, TOC/IRMS

Liège University – Dept. Biology Ecology Evolution

Liège University  – Freshwater and OCeanic science Unit of reSearch (FOCUS)

Institute of Chemistry (Building B6c), 13 Allée du 6 Août, Quartier Agora, Sart-Tilman Campus, 4000 Liège, Belgium

Contact
Gilles Lepoint
g.lepoint@uliege.be
32(0)43663327

Loïc Michel
loic.michel@uliege.be
32(0)43663322

Research line
Ecology

Topics
Food webs (mostly marine, but also freshwater or terrestrial), ecology, ocean sciences, environmental and earth sciences, plant and animal ecology and physiology, pollution & ecotoxicology

Isotopes
13C, 15N, 32S

Instruments
EA/C/IRMS, GC/C/IRMS

EA/IRMS, vario MICRO cube & IsoPrime precisION (Elementar)
GC/C/IRMS, Agilent 7890A & IsoPrime100 (Elementar)

Maastricht University – Human biology, Movement Sciences

Maastricht University – Human biology, Movement Sciences

PO Box 616, 6200 MD Maastricht
Universiteitssingel 50, 6229 ER Maastricht, NL

Contact
Luc van Loon
L.vanLoon@maastrichtuniversity.nl
31(0)433881397 /31(0)613260552

Ellen Blaak
e.blaak@maastrichtuniversity.nl

http://www.m3-research.nl
http://www.sirc.unimaas.nl

Research line
Health and Disease

Topics
protein, carbohydrate and fat and metabolism in vivo in humans
(nutritional) intervention studies
to assess substrate fluxes in different physiological situations and/or patient groups.

Isotopes
13C, 15N, 2H

Instruments
GC/C/IRMS, GC/MS

·        Thermo Scientific MAT-253 GC combustion IRMS
·        Agilent GC-MS (GC:7870A; MS:5975C) (Electron Impact mode)
·        Agilent GC-MS (GC: 6890N; MS: 5973) (EI- and CI-mode)
·        Finnigan DELTAplus GC combustion IRMS with detectors for CO2 and N2.

GC-C-IRMS:
·        Enrichment of breath CO2
·        Concentration and enrichment of CO2 in blood samples
·        Deuterated water enrichment
·        Enrichment of 13C-labeled glucose and fatty acids in plasma samples and muscle     extracts
·        Enrichment of 13C-labeled fatty acids in plasma FFA and plasma triglycerides and in the different lipid fractions of muscle
·        Enrichment of 13C- and 15N-labeled amino acids in plasma samples, in mixed muscle protein and albumin samples.

GC-MS:
·        Plasma enrichment of [2H5]glycerol, [U-13C]glycerol, [1-13C]KIC, [6,6-2H2]glucose,
[2H2]palmitate (enrichment in plasma FFA and triglycerides), [2H5-ring]phenylalanine, [1-13C]phenylalanine, [1-13C]leucine,
[1-13C]tyrosine [2H2]tyrosine and [2H4]tyrosine,
·        Concentrations of phenylalanine, tyrosine and leucine
·        [2H2]tyrosine
·        [U13C]phenylalanine
·        [2H5]phenylalanine
·        Intrinsically [1-13C]phenylalanine and [1-13C]leucine labeled milk protein
·        [2H2]glucose
·        [U13C]glucose
·        [2H2]palmitate
·        [U13C]palmitate
·        [2H5]-glycerol

Netherlands Forensic Institute – Microscopic Traces

Netherlands Forensic Institute – Microscopic Traces

PO Box 24044, 2490 AA Den Haag
Laan van Ypenburg  6, 2497 GB Den Haag

Contact
Gerard van der Peijl
g.van.der.peijl@nfi.minvenj.nl
31(0)708886478

Research line
Human forensics

Topics
Comparative analyses of different materials
mainly tapes, but also explosives, fibers, textiles,
paints, papers, inks, plastics or adhesives in general.

Isotopes
13C, 15N, 18O, 2H

Instruments
GC/C/IRMS/MS, EA/C/IRMS
GC-IRMS/MS (Agilent 7890 GC, ThermoFisher Mat 253 IRMS, ISQ Quadrupole MS, Interface ConFlo IV);
EA-IRMS (TC/EA und Flash EA 112, ThermoFisher Delta V advantage IRMS, Interface ConFlo IV)

Radboud University Nijmegen – General instruments

Radboud University Nijmegen – General instruments

Heyendaalseweg 135
6525 AJ Nijmegen, NL

Contact
Jelle Eygensteyn
J.Eygensteyn@science.ru.nl
31(0)243652755

Research line
Ecology

Topics
Experimental Plant Ecology
Environmental Science
Animal Ecology and Ecophysiology

Isotopes
13C, 15N

Instruments
EA/C/IRMS

Elemental analyser + DeltaPlus ( Finnigan)

Research Institute for Chromatography – Research & Development

Research Institute for Chromatography – Research & Development

Pres. Kennedypark 26
8500 Kortrijk, Belgium

Contact
Emmie Dumont
emmied@richrom.com
32(0)56204031

Research line
Analytical development

Topics
optimization of the chromatographic separation before IRMS
implementation of 2D-GC and 2D-LC
complex natural samples.

Isotopes
13C, 15N, 2H

Instruments
GC/Py/IRMS, 2D-GC/Py/IRMS, LC/C/IRMS

GC-C/Py-IRMS (Agilent GC 7890 + Thermo delta V advantage)
2D-GC-C/Py-IRMS
LC-C-IRMS (All Thermo)

RIKILT Institute of Food Safety – Cluster Authenticity and Nutrients (AN)

RIKILT Institute of Food Safety – Cluster Authenticity and Nutrients (AN)

PO Box 230, 6700 AE Wageningen
Akkermaalsbos 2
6708 WB Wageningen, NL

Contact
Saskia van Ruth
saskia.vanruth@wur.nl
31(0)317480250

Research line
Food Safety

Topics
to verify the authenticity of food and related agricultural commodities.
data interpretation and development of geospatial models (isoscapes)

Isotopes
13C, 15N, 18O, 2H, 34S

Instruments

No own instruments

RIKILT Institute of Food Safety – Department Growth Promoters (GB)

RIKILT Institute of Food Safety – Department Growth Promoters (GB)

PO Box 230, 6700 AE Wageningen
Akkermaalsbos 2, 6708 WB Wageningen, NL

Contact
Saskia Sterk
Saskia.Sterk@wur.nl
31(0)317480352

Marco Blokland
Marco.Blokland@wur.nl

Research line
Food Safety

Topics
developing analytical methods to identify abuse of growth promoters in animal husbandry
to distinguish endogenous natural hormones from illegally administered growth promoters (e.g. estrogens, androgens and corticosteroids)

Isotopes
13C

Instruments
GC/C/IRMS,  LC/C/IRMS

Thermo MAT 253 GC/C/IRMS (end of 2012)
LC Isolink interface future)